Skin patch coated in Covid-19 vaccine may work better than injections

‘Covid-19 vaccines in use today have to be stored at cold temperatures, but a patch covered in tiny plastic spikes coated in a vaccine could provide an alternative...

‘A skin patch for administering covid-19 vaccines gives greater immune protection than traditional injections, according to a study in mice. The patch can be stored at room temperature and be self-administered, making it suitable for use in places that lack cold storage facilities and medical staff.

‘Although covid-19 vaccines are now widely available in many countries, they have to be transported and stored at cold temperatures. “We wanted to come up with an alternative that would be stable long enough to go that last mile, especially in resource-limited settings,” says David Muller at the University of Queensland in Brisbane, Australia.’

Read here (New Scientist, Oct 29, 2021)

Denmark appears to have beaten Covid-19 — for now. Here’s how it did it.

‘As part of Denmark’s largest behavioral covid-19 research project (the HOPE project), we surveyed more than 400,000 individuals in Denmark and seven other countries. Our findings suggest that citizens’ high and stable trust in their health authorities has been a crucial factor in Denmark’s success. This trust, shown in the figure below, encouraged high vaccination rates and the successful implementation of key policies such as mass testing and coronavirus passports.’

Read here (Washington Post, Sept 20, 2021)

G20 health ministers aim to vaccinate 40% of global population against Covid-19 by end-2021

‘Health Minister Ong Ye Kung and his counterparts from the Group of Twenty (G20) are aiming to vaccinate at least 40 per cent of the world against COVID-19 by the end of the year. The target was announced at the G20 Health Ministers’ Meeting, held from Sunday (Sep 5) to Monday in Rome.

‘In a press release on Monday, Singapore's Ministry of Health (MOH) said the meeting had also adopted a Health Ministers’ Declaration emphasising the importance of strong multilateral collaboration in managing the COVID-19 pandemic and supporting global recovery, with the World Health Organization (WHO) taking a central and leading role. The health ministers also agreed that vaccination was key.’

Read here (Channel News Asia, Sept 6, 2021)

Israel and Chile both led on Covid jabs, so why is one back in lockdown?

‘Chile is in the enviable position of having vaccinated faster than any other country in the Americas. More than a third of the country’s 18 million people have received at least one shot of either Pfizer/BioNTech or China’s Sinovac Biotech vaccine. However, cases have soared to the point of overwhelming the health system and strict lockdown measures are back in place.

What went wrong in Chile?

‘The speedy vaccination programme appears to have instilled a false sense of security that led the country to ease restrictions too soon without people appreciating the ongoing risks. The country reopened its borders in November and in January introduced permits for Chileans to go on summer holiday. Without strict controls on people entering the country, and the lack of an efficient contact-tracing system, travellers may have brought infections back into the country that were not picked up.’

Read here (The Guardian, Apr 6, 2021)

New Covid variants have changed the game, and vaccines will not be enough. Lancet Covid-19 Commission calls for global ‘maximum suppression’

‘Put simply, the game has changed, and a successful global rollout of current vaccines by itself is no longer a guarantee of victory... No one is truly safe from COVID-19 until everyone is safe. We are in a race against time to get global transmission rates low enough to prevent the emergence and spread of new variants. The danger is that variants will arise that can overcome the immunity conferred by vaccinations or prior infection.

‘What’s more, many countries lack the capacity to track emerging variants via genomic surveillance. This means the situation may be even more serious than it appears.

‘As members of the Lancet COVID-19 Commission Taskforce on Public Health, we call for urgent action in response to the new variants. These new variants mean we cannot rely on the vaccines alone to provide protection but must maintain strong public health measures to reduce the risk from these variants. At the same time, we need to accelerate the vaccine program in all countries in an equitable way. Together, these strategies will deliver “maximum suppression” of the virus.’

Read here (The Conversation, Apr 6, 2021)

Download report here (Lancet Covid-19 Commission Taskforce on Public Health,  March 2021)

Vaccinating Asia: How does world's largest continent immunise 4.5 billion people in shortest time possible?

‘It is a critical issue as the world rushes to achieve herd immunity against the coronavirus. How does the largest continent in the world immunise 4.5 billion people in the shortest time possible? The Straits Times bureaus find out in this special report.’

• Grappling with myriad challenges on path towards Covid-19 immunity
• Midwives and soldiers in Indonesia mobilised to support country's inoculation drive
• Millions of undocumented migrants in Malaysia keen on Covid-19 jab but wary of arrest
• Filipinos in search of coveted 'Covid-19 passport'
• India's greatest challenge lies in vaccinating rural villages
• Quality and quantity of Covid-19 vaccines in China hamper inoculation drive
• Hong Kong's Covid-19 vaccination drive zips ahead despite woes
• South Korean govt draws flak for not mandating Covid-19 vaccine holiday after roll-out delay
• South Korean man, Singaporean fiancee inoculated ahead of May wedding
• Japan's chequered past with vaccines raises fresh fears
• No rush for Covid-19 jab in Taiwan, given fears over side effects
• Religious, community groups, experts clear doubts about Covid-19 jabs in Singapore
• Church webinar in S'pore convinces senior to take Covid-19 jab
• Tapping TikTok videos and social media influencers to spread information on vaccines in Singapore
• MCI officers create skits, dances on TikTok to debunk Covid-19 myths
• Foodcourt chat to allay fears about Covid-19 shots among Singaporeans

Read here (Straits Times, Apr 2, 2021) 

Khairy: Next phase of Malaysia’s Covid-19 vaccine plan to start April 19, eligible recipients to get two weeks’ notice for appointments

‘Phase two of the National Covid-19 Immunisation Programme (PICK) will kick off on April 19, with appointment reminders sent out to eligible recipients two weeks ahead. Minister of Science, Technology and Innovation Khairy Jamaluddin said a total of 2 million people — senior citizens, high-risk groups, the chronically ill, and people with disabilities — have so far registered for vaccination under the second phase.

“We will begin issuing appointment notices through instant messaging, phone calls and MySejahtera to those who have been chosen to be listed under this second phase on April 5,” he told a press conference here. The second phase of the National Covid-19 Immunisation Programme is expected to be carried out from April to August.’

Read here (Malay Mail, Mar 29, 2021)

Malaysia to allow private hospitals to procure Covid-19 vaccines, run parallel vaccination drive in second half of 2021

‘Malaysia will allow its private healthcare providers to open negotiations to procure their own Covid-19 vaccine supplies, the government said on Monday (March 29).

‘However, the country's coordinating minister for its immunisation programme, Mr Khairy Jamaluddin, tempered expectations by warning that a private sector vaccine roll-out - which would allow individuals to pay for their own Covid-19 vaccine - might take place only in the second half of 2021.

‘Mr Khairy said that he would hold discussions with private hospitals about allowing them to procure vaccines, following a request by the Association of Private Hospitals of Malaysia (APHM) to run a parallel vaccination drive along with the government's free vaccination programme to help the country achieve herd immunity against the coronavirus.’

Read here (Straits Times, Mar 29, 2021)

What it will take to vaccinate the world against Covid-19

‘A special report outlines the challenges — from unleashing the power of mRNA vaccines, to the battle for temporary relief on intellectual-property rights...

‘In the long term, argues Friede, every region needs a facility that fully owns the production know-how and can produce vaccines. The gap is most egregious in Africa, a continent that imports 99% of its vaccines, says Nkengasong. It has only three big vaccine manufacturers. “Can a continent of 1.2 billion — projected to be 2.4 billion in 30 years, where one in four people in the world will be African — continue to import 99% of its vaccines?” Nkengasong asks.’

Read here (Nature, Mar 25, 2021)

World Bank support for Covid-19 vaccination fails to ensure equitable access

• World Bank rolls out $12 billion programme to support global Covid-19 vaccination
• New report finds that wider Bank pandemic programme does not ensure free access to health care
• World Bank fails to address key challenges to universal and equitable access to vaccines in Global South

Read here (Bretton Woods Project, Mar 23, 2021)

Mark Zuckerberg announces Facebook's plans to help get people vaccinated against Covid-19

‘Today we're launching a global campaign to help bring 50 million people a step closer to getting Covid-19 vaccines. 

‘We've already connected over 2 billion people to authoritative Covid-19 information. Now that many countries are moving towards vaccinations for all adults, we're working on tools to make it easier for everyone to get vaccinated as well. 

‘First, we're launching a tool that shows you when and where you can get vaccinated and gives you a link to make an appointment. This will be in the Covid Information Center, which we'll show people right in their News Feed. We've already seen people use Facebook to find vaccination appointments, so this should enable millions more people to do the same.

‘Second, we're bringing the Covid Information Center to Instagram, and we'll show it to people prominently there too. 

‘Third, we're working with health authorities and governments to expand their WhatsApp chatbots to help people register for vaccines. More than 3 billion messages related to Covid have already been sent by governments, non-profits and international organizations to citizens through official WhatsApp chatbots, so this update will help with the vaccination effort as well.’

Read here (Facebook, Mar 15, 2020)

After a year of MCO, recovery is in sight

‘On March 18, 2020, the first Movement Control Order (MCO) was imposed and there was much uncertainty among the public and business community over what would happen next. One year on, the SARS-CoV-2 virus has taken 1,177 lives and infected 314,989 people in the country (as at March 10). Despite the grim circumstances, many see light at the end of the tunnel as Malaysia rolls out its National Covid-19 Immunisation Programme (NCIP).

‘Speaking to experts, we identify three main areas that beckons attention — healthcare, economy and last but not least politics. Covid-19 is still raging on globally, and the challenge is to vaccinate the community as quickly as possible so as to not allow the more transmissible variants to get a foothold in the community. Meanwhile, vaccine effectiveness is seen as one key driver for economic recovery. When that has effectively been executed, the focus should be on repairing the damage that has been caused by the pandemic.

‘Many also believe that political stability is one challenge Malaysia will face. There is a need to exit from the emergency rule and for the country to be given a clear mandate from a stable government.

‘In the accompanying stories, we take a look at the winners and losers in the post-pandemic era. Will pandemic winners such as the glove and technology players continue to prosper? Will the tourism, retail, hospitality and manufacturing industries as well as small and medium enterprises move away from the dire conditions brought on by Covid-19 anytime soon?

‘Nonetheless, it has been a fruitful year for local equities since the pandemic outbreak, with healthcare and technology stocks being the top gainers. What can we expect for the rest of the year after stock prices for most sectors rebounded significantly from their lows last year? We speak to heads of research to find out what they think about the market direction.’ 

Get the full story in this week’s issue of The Edge Malaysia.

Read here (The Edge, Mar 13, 2021)

Home Ground: Ethical issues in Covid-19 vaccine roll-outs

‘A principled and pragmatic approach to securing and allocating Covid-19 vaccines works best... ‘Every vaccination programme carries with it ethical concerns over, among other things, safety, efficacy and how to distribute and allocate the vaccine when there are limited supplies...

‘A vaccine programme in the middle of a global pandemic is even trickier. On the one hand, speedy access to the vaccine can make the difference between life and death. On the other hand, the vaccines for Covid-19 are new and relatively untested: The world is learning of side effects as millions more get jabbed; and while we know the short-term efficacy, no one knows how long the protection lasts.

‘As Prof Lim said at the webinar, rolling out vaccination in the middle of a public health emergency is like chasing after a moving target. This requires constant monitoring and updating of rules and plans.’

This account also discusses, in the Singapore context: (1) The race to get hold of supplies (2) Who gets jabbed first and why (3) Why giving a choice of vaccine is not a good idea.

Read here (Straits Times, Mar 12, 2021)

The catch to ‘free’ Covid-19 vaccination by private hospitals – P Gunasegaram

‘I read with great interest the story that private hospitals are prepared to help the government inoculate people against Covid-19 – and here’s the curious part – by disseminating the vaccine without charge. Yes, you read that right. But if the government is not careful, it may end up giving private hospitals windfall gains of over half a billion ringgit, as we shall show.

‘It was reported that this will be for vaccines procured by the government, with private hospitals appointed as implementers of the free jabs...’

Read here (The Vibes, March 11, 2021)

Khairy welcomes private sector procuring approved Covid-19 vaccines

“With regards to the purchase of vaccines by the private sector, as I have mentioned yesterday, most of the vaccine manufacturers only carry out negotiations with governments,” Khairy responded to Najib in a comment on his Facebook post...

“But if there are private parties who are able to carry out negotiations with vaccine manufacturers, especially those that have received approval from the NPRA (National Pharmaceutical Regulatory Agency) (Pfizer, AstraZeneca, and Sinovac), please do so. I really welcome it,” added the science, technology and innovation minister. 

‘Previously, Malaysian-based pharmaceutical company Pharmaniaga Bhd announced that it planned to sell some of its Sinovac vaccine doses to the private sector. Pharmaniaga is undertaking the fill-and-finish processing of Sinovac’s vaccine. Solution Biologics, the distributor of Chinese CanSino’s vaccine, has also expressed plans to supply private health care providers with the vaccine, on top of selling 3.5 million doses to the Malaysian government.’ 

Read here (Code Blue, Mar 10, 2021)

The new normal (Phase 2)

‘So, we’re almost a year into the “New Normal” (a/k/a “pathologized totalitarianism”) and things are still looking … well, pretty totalitarian. Most of Western Europe is still in “lockdown,” or “under curfew,” or in some other state of “health emergency.” Police are fining and arresting people for “being outdoors without a valid reason.”  Protest is still banned. Dissent is still censored.

‘The official propaganda is relentless. Governments are ruling by edict, subjecting people to an ever-changing series of increasingly absurd restrictions of the most fundamental aspects of everyday life.

‘And now, the campaign to “vaccinate” the entirety of humanity against a virus that causes mild to moderate flu-like symptoms or, more commonly, no symptoms at all, in over 95% of those infected, and that over 99% of the infected survive (and that has no real effect on age-adjusted death rates, and the mortality profile of which is more or less identical to the normal mortality profile) is being waged with literally religious fervor.

“Vaccine passports” (which are definitely creepy, but which bear no resemblance to Aryan Ancestry Certificates, or any other fascistic apartheid-type documents, so don’t even think about making such a comparison!) are in the pipeline in a number of countries. They have already been rolled out in Israel.’

Read here (OffGuardian, Mar 9, 2020)

Can vaccinated people transmit COVID-19? The answer will be key to ending the pandemic

‘There’s been positive news about how effective the vaccines might be in preventing transmission—but as several experts note, some studies that have been made public so far are inconclusive. Until we have a better answer on transmission, social distancing, hand hygiene, testing, and mask wearing will remain important in the fight to limit and eventually end the pandemic.

‘A recent, unpublished Israeli study showed a nearly 90 percent reduction in infections among the vaccinated population. Wired magazine writer Megan Molteni noted that the media framing of the study may have been overly optimistic. While the headlines about this unpublished study were wildly enthusiastic, the reality is more nuanced.  “Israel finds BioNTech/Pfizer vaccine reduced virus transmission,” read one headline. But Eric Topol, a professor of molecular medicine at Scripps Research, told Wired he was skeptical about drawing any conclusions about the extent to which the Pfizer vaccine cut transmission rates. He told the magazine that to accurately study asymptomatic transmission, both vaccinated and unvaccinated people should be regularly tested. “The testing rates were such a hodgepodge, I don’t know you can make any conclusions about how much the vaccine cut transmission in Israel, let alone assigning a number as concrete as 89.4 percent,” he told Molteni.’

Read here (Bulletin of the Atomic Scientists, March 9, 2021)

Will I have to wear a mask after getting the Covid vaccine? The science explained

‘Public health authorities want people to keep wearing masks and social distancing, even after they receive a vaccine. This might seem counterintuitive – after all, if someone gets a vaccine, aren’t they protected from the coronavirus?

‘The answer is complicated: the vast majority of people who are vaccinated will be protected from Covid-19, the disease caused by the SARS-CoV-2 virus. However, vaccinated people may still be able to transmit the virus, even though they do not display any symptoms. “We know now the vaccines can protect, but what we haven’t had enough time to really understand is – does it protect from spreading?” said Avery August, professor of immunology at Cornell University.

‘That is because the the SARS-CoV-2 virus may still colonize the respiratory tract, even as systemic immune cells protect the overall body from the disease it causes – Covid-19.’

Read here (The Guardian, Feb 26, 2021)

Khairy: Non-citizens to receive free Covid-19 vaccines to ensure everyone is safe

‘Malaysia will only be safe from the Covid-19 pandemic if the people, including foreign citizens living here, receive the vaccines, said Science, Technology and Innovation Minister Khairy Jamaluddin. He said that even if Malaysians were to receive the vaccines, it would not mean they are safe because Malaysia has about three million foreigners who are likely to cause the virus to spread and infect Malaysians.

“That is why this (giving free vaccines to non-citizens) needs to be done because we are not safe until everyone is safe. In vaccine science, if there are more vaccine recipients, then we are safe and the virus cannot infect others. As such, we are targeting 80 per cent of the population to create group immunity and form enough antibodies so that the virus does not infect people in the country. If we (locals) are the only recipients, we will not be safe because they (foreigners) may still infect us, or the virus could spread among the foreigners. That is why it is important that we protect everyone. This is the right decision for the sake of humanity,” he said.’

Read here (Malay Mail, Feb 12, 2021)

Online scammers are rushing to exploit people desperate to get the Covid-19 vaccine

‘Many Americans are eager to get the Covid-19 vaccine as quickly as possible. But that inevitably means there are scammers ready to use the internet to take advantage of these vaccine seekers to steal their money and personal information.

‘Similar to earlier in the pandemic, when fraudsters flooded the internet with ads for sketchy “cures,” bogus Covid-19 tests, and scarce personal protective equipment, online schemers are now selling fake vaccine appointments and knockoff vaccine cards. (These cards document the date that vaccinated people received their doses, the manufacturer of their vaccine, and its batch number; they’re seen as a record of vaccination.)

‘Vaccine schemes are alarming. In late January, one man in Washington state was arrested after advertising fake Covid-19 vaccines online for as much as $1,000, and even injected people with an unknown substance, according to the Department of Justice, which is investigating these types of fraud cases.’

Read here (Vox, Feb 11, 2021)