Khairy welcomes private sector procuring approved Covid-19 vaccines

“With regards to the purchase of vaccines by the private sector, as I have mentioned yesterday, most of the vaccine manufacturers only carry out negotiations with governments,” Khairy responded to Najib in a comment on his Facebook post...

“But if there are private parties who are able to carry out negotiations with vaccine manufacturers, especially those that have received approval from the NPRA (National Pharmaceutical Regulatory Agency) (Pfizer, AstraZeneca, and Sinovac), please do so. I really welcome it,” added the science, technology and innovation minister. 

‘Previously, Malaysian-based pharmaceutical company Pharmaniaga Bhd announced that it planned to sell some of its Sinovac vaccine doses to the private sector. Pharmaniaga is undertaking the fill-and-finish processing of Sinovac’s vaccine. Solution Biologics, the distributor of Chinese CanSino’s vaccine, has also expressed plans to supply private health care providers with the vaccine, on top of selling 3.5 million doses to the Malaysian government.’ 

Read here (Code Blue, Mar 10, 2021)

Malaysia vaccinates one third of frontliners within fortnight

‘A third of 500,000 frontliners have received their first dose of the Covid-19 vaccine, some three weeks before the targeted vaccination completion by March 31. As of March 8, a total of 166,363 frontliners have received their first dose of the coronavirus vaccine, achieving 33.3 per cent of the national Covid-19 immunisation programme’s Phase One target in 13 days after the vaccines were rolled out from February 24.

‘If the current pace continues, the government will need another 26 days to administer at least the first dose to all 500,000 frontline workers, just slightly missing the March 31 target by three days.’ 

Read here (Code Blue, Mar 9, 2021)

Germany approves AstraZeneca vaccine for over-65s

‘Germany's vaccine commission has approved the use of the Oxford-AstraZeneca jab in people aged over 65. The country previously approved it for under-65s only, citing insufficient data on its effects on older people. That led to public scepticism about its effectiveness, with some Germans spurning it and leaving many doses unused.

‘But German Chancellor Angela Merkel said recent studies had now provided enough data to approve it for all ages. Announcing the commission's decision on Thursday, Health Minister Jens Spahn said the move was "good news for older people who are waiting for an injection".’

Read here (BBC, Mar 5, 2021) 

Don’t let private hospitals jump the vaccination queue ― no special privileges for the rich! ― Suaram

‘Suara Rakyat Malaysia (Suaram) believes that the commercialisation of the Covid-19 vaccination by the private hospitals would only encourage “queue-cutting” where the rich and powerful stands to gain and potentially undermine the government's national programme and weakens social solidarity.

‘Furthermore, allowing private hospitals to procure vaccines and subsequently running their own vaccination programme also contradicts the principles of giving everyone an equal opportunity in the country’s largest vaccination programme ever.’

Read here (Malay Mail, March 3, 2021)

Malaysia approves Sinovac, AstraZeneca Covid-19 vaccines for use

‘Malaysia on Tuesday (Mar 2) granted conditional approval for the use of vaccines made by UK firm AstraZeneca and China's Sinovac, just days after launching its nationwide COVID-19 inoculation programme. Malaysia began its vaccination drive on Feb 24 using a shot developed by US drugmaker Pfizer and German partner BioNTech, as it tries to rein in a spike in infections and help revive an economy that recorded its worst slump in more than two decades last year.’

Read here (Channel News Asia, Mar 2, 2021)

The scientist who’s been right about Covid-19 vaccines predicts what’s next

‘[Hilda] Bastian — an expert in analyzing clinical trial data, founding member of the Cochrane Collaboration, and a former National Institutes of Health official — has gone down rabbit holes before. There was the time she traveled the US on her own dime to research and take historical photos for a Wikipedia list of African American mathematicians.

‘But her obsession with vaccines in this pandemic has been especially fruitful: She’s called the race right at just about every turn...

‘Nearly a year into her project, I caught up with Bastian to ask where our blind spots are now and how she predicts the vaccine story — and the pandemic — will unfold. She talked about the need for health officials to acknowledge that coronavirus vaccines have potentially “big differences in efficacy and adverse events,” a time in the future when we may need Covid-19 vaccine boosters every year, and the problem of people in rich countries like the US shamelessly hogging vaccines.’

Read here (Vox, Feb 24, 2021)

Why kids need their own Covid-19 vaccine trials

‘Adolescents are being tested now. Younger children will be next. Why did vaccine manufacturers wait to study them?...

‘The U.S. Food and Drug Administration requires that new vaccines be independently studied in children. Children’s immune systems are still maturing and are unpredictable, so they might react to the coronavirus differently or have side effects that don’t occur in adults. “They might respond better or worse,” says James Campbell, professor of pediatrics at the University of Maryland School of Medicine’s Center for Vaccine Development and Global Health. “Until you do the study with the vaccine, you don’t know what will happen.”

Read here (National Geographic, Feb 20, 2021)

Experts answer the biggest Covid vaccine questions

‘The lack of informed messaging from the Trump administration, combined with the range of different COVID vaccines, the emergence of new coronavirus variants, and inconsistent state and municipal rollout plans, have caused confusion and driven vaccine hesitancy. Scientific American asked Namandjé Bumpus, a pharmacologist at Johns Hopkins Medicine in Baltimore, and Ashley Lauren St. John, an immunologist at Duke-NUS Medical School in Singapore to answer some of the biggest questions about the currently available COVID vaccines:

• Should you get an authorized COVID vaccine now if you are eligible?
• Should you get vaccinated if you have already had COVID?
• How should you interpret vaccine efficacy—what does “95 percent efficacy” or “66 percent efficacy” even mean?
• If you get the vaccine and still get infected, does the vaccine still make a difference? 
• Will it prevent severe disease or death?
• Do the vaccines protect against the new virus variants, including those first identified in the U.K., South Africa and Brazil?
• What is the difference between mRNA and viral vector vaccines?
• Is there a “best” vaccine?
• Will the vaccine protect you from giving the virus to others?
• Will the vaccine’s effectiveness “wear off” over time?
• Should you be worried about allergic reactions to the vaccine?
• How can you ensure you’re getting a legitimate, authorized vaccine?

Read here (Scientific American, Feb 19, 2021)

A quite possibly wonderful summer

‘The summer of 2021 is shaping up to be historic... After months of soaring deaths and infections, COVID-19 cases across the United States are declining even more sharply than experts anticipated. This is expected to continue, and rates of serious illness and death will plummet even faster than cases, as high-risk populations are vaccinated. Even academics who have spent the pandemic delivering ominous warnings have shifted their tone to cautiously optimistic now that vaccination rates are exploding.’

Read here (The Atlantic, Feb 19, 2021)

Private hospitals to work with govt in vaccine rollout

‘Private hospitals across the country say they are ready to work with the government in vaccinating the public to speed up the National Covid-19 Immunisation Programme.

‘Association of Private Hospitals of Malaysia (APHM) president Dr Kuljit Singh said the group was waiting to discuss the mechanism of the programme as “many would be happy to be vaccinated in private hospitals”. “It is a service we can provide for the public. However, we are waiting for further instructions,” he said in a statement.’

Read here (Free Malaysia Today, Feb 16, 2021)

As vaccinations lag, Israel combats online misinformation

‘After surging ahead in the race to vaccinate its population against the coronavirus, Israel is blaming online misinformation for a sudden slowdown in the campaign. Now, officials are fighting back.

‘Israel’s Health Ministry, which is spearheading the vaccination efforts, is employing both warnings and incentives as it tries to persuade reluctant holdouts to get immunized. It has beefed up a digital task force to counter spurious claims about the vaccines, while local governments are turning to DJs and free food to lure people to vaccination centers. Concerts and museums could soon be off limits to the unvaccinated.’

Read here (AP, Feb 15, 2021)

Khairy: Non-citizens to receive free Covid-19 vaccines to ensure everyone is safe

‘Malaysia will only be safe from the Covid-19 pandemic if the people, including foreign citizens living here, receive the vaccines, said Science, Technology and Innovation Minister Khairy Jamaluddin. He said that even if Malaysians were to receive the vaccines, it would not mean they are safe because Malaysia has about three million foreigners who are likely to cause the virus to spread and infect Malaysians.

“That is why this (giving free vaccines to non-citizens) needs to be done because we are not safe until everyone is safe. In vaccine science, if there are more vaccine recipients, then we are safe and the virus cannot infect others. As such, we are targeting 80 per cent of the population to create group immunity and form enough antibodies so that the virus does not infect people in the country. If we (locals) are the only recipients, we will not be safe because they (foreigners) may still infect us, or the virus could spread among the foreigners. That is why it is important that we protect everyone. This is the right decision for the sake of humanity,” he said.’

Read here (Malay Mail, Feb 12, 2021)

Khairy: Registration for Covid-19 vaccination to start in March

‘Registration for Covid-19 vaccination to members of the public is expected to kick off in March and this will be on a volunteer basis, said Science, Technology and Innovation Minister Khairy Jamaluddin. 

He said there are five ways for the public to sign up for the vaccine, including via the MySejahtera application. “If they have no access to MySejahtera, they may go to the JKJAV (Covid-19 Vaccine Supply Access Guarantee Special Committee) website, which will be launched by the prime minister next week.

“In addition there is the hotline (number to be fixed later), manual registration at public and private clinics and hospitals, and lastly, for people living in the rural areas, we will be working with the state government to get them to register the recipients including senior citizens,” he said during the Ruang Bicara programme aired on Bernama TV, yesterday...

‘The first phase, from February to April, is for the 500,000 frontliners who are directly involved in the fight against Covid-19, while the second phase, from April to August, for the high-risk group, comprising senior citizens aged 60 and above and the vulnerable group with morbidity problems, such as heart disease, obesity, diabetes and high blood pressure, as well as persons with disabilities (PwD).

‘The third phase is from May to February next year and it is for those aged 18 and above.’

Read here (Malay Mail, Feb 12, 2021)

How to manage vaccine liability in Malaysia

‘While different systems vary in terms of elements of compensation and funding mechanisms, we can adapt the policies related to funding, proving injury and distributing compensation involving multiple parties. For example, we can set up a bespoke Covid-19 vaccine compensation programme. The programme could be co-financed by a mixture of public and private funds (eg. led by insurers), to achieve effective immunisation roll-out while providing a fair and equitable remedy and reduce overall costs to society.  

‘Two, Malaysia’s government can adapt the Singapore model and completely assume the financial costs of any serious adverse events from the vaccine. The list of serious adverse events that are covered, the mechanism of approval and the ministry which will pay are details that can be decided by a relevant committee. Given serious adverse events are rare, the overall cost should be manageable and represents a good investment for public confidence.

‘A third option is the Covax Facility’s no-fault-compensation scheme for indemnification and liability. The scheme proposed by Covax aims to set up a compensation fund for vaccine recipients in participating countries who might suffer any side-effects from COVID-19 vaccines. The scheme proposes a new mechanism to pay a lump-sum based on severity of harm to victims from Covid-19 vaccines associated side effects. The proposed mechanism would be funded by earmarking funds from high income countries or by charging taxes on pharmaceutical companies.  

‘There are reasonable solutions to the problem, and Malaysia must have a full-frontal and honest conversation about how to manage adverse events, no matter how unlikely they might be. All the solutions described above are not mutually exclusive. However, implementing them requires political will and courage. Covid-19 vaccination is a collective national effort, and we must do all we can to increase public confidence in the vaccine by providing appropriate liability protections.’

Read here (Malay Mail, Feb 11, 2021) 

‘Pure, liquid hope’: What the vaccine means to me as a GP

‘Clinicians everywhere are all nervous about what will happen if that loosening of restrictions occurs too quickly. Though death from Covid among the under-50s is relatively rare, it can still be a terrible, terrifying disease, capable of rendering its victims breathless and exhausted for weeks (and in some cases, months) after its fevers have run their course. One of my own patients, a nurse in his 20s, used to run 10km three or four times a week. The staff vaccination programme was too late for him: he caught Covid on the wards just before Christmas. Though he’s now back at work, he still hasn’t recovered sufficiently to be able to get back to running.

‘For the next six months, all my colleagues and I will be vaccinating as needed, as many hours as we’re able to. This week I’ve been gladly trudging the streets in the snow, vaccinating our housebound patients, and there aren’t too many still to go. In Scotland, the programme is anticipated to go on at least until 31 July, and the hope is that everyone over 50 will have had a first dose by May.

‘The numbers are daunting, but there’s a spirit of anticipation and celebration in the air. Many are starting to dare to plan for a world post-Covid, and I’m tempted to share that optimism. Opening my first box of vials, I thought of a friend in Orkney, a GP who’d already vaccinated all the over-80s of his practice, and who’d begun to call in the over-70s. We met briefly in Kirkwall, outdoors, on my journey from Orkney back to Edinburgh. “How did it feel to get started?” I asked him.

“I almost wept as I opened that box of vials,” he said, smiling at the memory. “Each one was hope – pure, liquid hope.”

Read here (The Guardian, Feb 11, 2021)

Trust in Covid vaccines is growing

‘Attitudes towards COVID-19 vaccines seem to be improving in some parts of the world, a survey of thousands of people in 15 countries has found. Researchers have welcomed the results, which suggest that an increasing proportion of people are willing to be immunized. But they caution that some problems persist, such as concerns about vaccine safety. “For the first time since the pandemic began, I can sense that optimism is spreading faster than the virus,” says behavioural scientist Sarah Jones at Imperial College London, who co-led the global attitudes towards a COVID-19 vaccine survey.

‘The survey is part of the COVID-19 behaviour tracker, run by Imperial together with the UK market-research company YouGov.’

Read here (Nature, Feb 10, 2021)

Safely reopening requires testing, tracing and isolation, not just vaccines

‘The Moderna and Pfizer vaccines were developed in record time. However, these announcements highlight significant challenges: delivering two-dose vaccines with stringent cold-chain requirements to almost eight billion people, many of whom reside in communities with underfunded and strained health systems, is no small feat. Even if we address the logistical challenges, the reality is that it takes time and funding to deliver vaccines, treatments and tests that reach everyone in need. It is a sobering reminder that when lifesaving antiretrovirals were introduced for HIV-positive people, it took seven years before the medicine reached the poorest communities. And during that time, millions of people died, and millions more were infected, and the HIV pandemic continued to grow.

‘Until we can overcome these obstacles and ensure equitable delivery of vaccines and treatments once available across the globe, the fundamentals of controlling this virus remain as important as ever.

‘For a long time, many countries will continue to rely on already proven tools to control the pandemic. The formula is simple: test, trace and isolate. This straightforward but effective process is key to safely reopening economies and societies. It is made possible through the rapid and equitable scale-up of diagnostics, which have proven to be the most important tool for limiting the spread of COVID-19. Test, trace and isolate—and ultimately test, trace and treat once more treatments become available—is an efficient, sustainable way to control the virus, especially in contrast to last-resort emergency lockdown measures, which can erode the public support and trust necessary for the success of many other helpful public health measures, including vaccination and mask-wearing.

‘We have seen this strategy implemented successfully around the world for decades with age-old diseases like tuberculosis. This strategy is also making a difference in the fight against COVID-19.’

Read here (Scientific American, Feb 9, 2021)

Israel is the world’s most vaccinated country. Why are cases rising?

‘Rahav [Galia Rahav, the head of the infectious-disease unit at Tel Aviv’s Sheba Medical Center] attributes the soaring rate of infection in the general population to the weariness of Israelis — on their third or fourth lockdown, depending on how you count — with having their children at home, restrictions limiting them to 1,000 yards from their homes, and of the “politicization” of the ever-shifting rules of confinement.

‘Like many other countries, Israel launched its vaccination campaign with the two most vulnerable sectors: frontline medical workers and citizens over the age of 65. In January, as jubilant grandparents and ambulance drivers got vaccinated, and slowly stopped falling ill, younger and less cautious Israelis flouted caution — turning themselves into spreaders just as the highly infectious British mutation of the virus wafted into the country.’

Read here (New York magazine, Feb 7, 2021)

Vaccines are curbing Covid: Data from Israel show drop in infections

‘Close to 90% of people aged 60 and older in the country have received their first dose of Pfizer’s 2-dose vaccine so far. Now, data collected by Israel’s Ministry of Health show that there was a 41% drop in confirmed COVID-19 infections in that age group, and a 31% drop in hospitalizations from mid-January to early February. In comparison, for people aged 59 and younger — of which just more than 30% have been vaccinated — cases dropped by only 12% and hospitalizations by 5% over the same time. The figures are based on analysis of roughly a quarter of a million COVID-19 infections.’

Read here (Nature, Feb 5, 2021)

Sinovac applies for conditional approval of Covid-19 vaccine in China

‘China's medicine regulator is reviewing a second domestically developed COVID-19 vaccine for conditional approval. The CoronaVac inoculation, developed by Sinovac Biotech, has been given to tens of thousands of people in China under an emergency use program launched in July targeting specific groups with high infection risks. Regulators are also reviewing for approval a similar vaccine created by state-owned China National Pharmaceutical Group, known as Sinopharm...

‘China's COVID-19 vaccines have won approval in a dozen countries for emergency use, but the failure to publish detailed trial data could undermine public trust, a leading Chinese researcher said in a recent interview.

‘Ding Sheng, dean of Tsinghua University's School of Pharmaceutical Sciences and director of the Global Health Drug Discovery Institute (GHDDI), called for the original clinical trial data from Chinese experimental vaccines to be made public so that experts can better assess their efficacy and eliminate lingering safety concerns in China and abroad.’

Read here (Nikkei, Feb 4, 2021)